A single 150 mg oral dose is the standard fluconazole dosage for uncomplicated vaginal yeast infections, while 200 mg daily is used for infections in the mouth, esophagus, or deeper tissues. The typical Diflucan dosage for adults ranges from 50 mg to 400 mg daily. The oral tablet is most common, but if you have difficulty swallowing medications, the oral suspension is another option. The dose is usually 12 milligrams (mg) per kilogram (kg) of body weight on the first day, followed by 6 mg per kg of body weight once a day, for at least 10 to 12 weeks. Detailed Fluconazole dosage information for adults and children. Includes dosages for Vaginal Candidiasis, Onychomycosis - Toenail, Oral Thrush and more; plus renal, liver and dialysis adjustments. Diflucan Dosage and Administration Adult All doses are once daily. Oropharyngeal candidiasis: 200mg on Day 1, then 100mg/day for at least 2 weeks. Medscape - Candidia infection dosing for Diflucan (fluconazole), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost. Diflucan (fluconazole) is a widely used antifungal medication with various dosing schedules depending on the type of infection and the patient's age. Typical adult doses range from a single 150 mg dose for vaginal yeast infections to daily doses up to 400 mg for serious fungal infections. Another study at a 400 mg and 800 mg daily dose of fluconazole demonstrated that fluconazole taken in doses of 400 mg/day or greater significantly increases plasma levels of terfenadine when taken concomitantly. Medically reviewed guide to fluconazole (Diflucan) dosages. Find typical strengths for adults and children, treatment lengths, and tips for taking oral tablets safely. Detailed dosage guidelines and administration information for Diflucan (fluconazole). Includes dose adjustments, warnings and precautions.